polars-bio

- **bioframe_migration.md** - Operation mapping table, API differences, performance comparison, migration code examples, and pandas compatibility mode.

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---
name: polars-bio
description: High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap, nearest, merge, coverage, complement, subtract for BED/VCF/BAM/GFF intervals. Streaming, cloud-native, faster bioframe alternative.
license: https://github.com/biodatageeks/polars-bio/blob/main/LICENSE
metadata:
    skill-author: K-Dense Inc.
---

# polars-bio

## Overview

polars-bio is a high-performance Python library for genomic interval operations and bio...

Full prompt length: 14052 characters

Tools & Technologies

• python
• Python
• Azure